What is Myalept powder
Firstly, Buy Myalept Subcutaneous powder , Order Myalept Powder Online, Myalept metreleptin Online Cost,Cheap Metreleptin Powder, Myalept (metreleptin), a prescription medication, is a leptin replacement therapy used with a doctor-recommended diet to treat problems caused by not having enough leptin (leptin deficiency) in people with generalized lipodystrophy.
Dosage Forms & Strengths
Secondly, lyophylized powder for reconstitution
- 11.3mg (5mg/mL when reconstituted with 2.2 mL water for injection)
Lipodystrophy
Hence, Indicated as replacement therapy (in addition to diet) for the complications of leptin deficiency in patients with congenital generalized or acquired generalized lipodystrophy
Therefore, Administer by SC injection once daily at the same time each day
≤40 kg (males or females)
- Initial daily dose: 0.06 mg/kg (0.012 mL/kg) SC
- Dose adjustments: 0.02 mg/kg (0.004 mL/kg)
- Maximum daily dose: 0.13 mg/kg (0.026 mL/kg)
Males >40 kg
- Initial daily dose: 2.5 mg (0.5 mL) SC
- Dose adjustments: 1.25-2.5 mg (0.25-0.5 mL)
- Maximum daily dose: 10 mg (2 mL) Cheap Metreleptin Powder
Females >40 kg
- Initial daily dose: 5 mg (1 mL) SC
- Dose adjustments: 1.25-2.5 mg (0.25-0.5 mL)
- Maximum daily dose: 10 mg (2 mL)
Dosage Modifications
Coadministration with insulin or insulin secretagogue (eg, sulfonylurea, meglitinide derivatives): Dosage adjustments, including possible large reductions, of insulin or insulin secretagogue may be necessary in some patients to minimize the risk of hypoglycemia. Buy Myalept Subcutaneous powder
Dosing Considerations
Safety and efficacy not established for
- Treatment of complications of partial lipodystrophy
- Treatment of liver disease, including nonalcoholic steatohepatitis (NASH)
- HIV-related lipodystrophy
- Use in patients with metabolic disease, including diabetes mellitus and hypertriglyceridemia, without concurrent evidence of generalized lipodystrophy
Discontinuing due to pancreatitis risk
- When discontinuing therapy in patients with risk factors for pancreatitis (eg, history of pancreatitis, severe hypertriglyceridemia), taper the dose over a 1-week period
- During tapering, monitor triglyceride levels and consider initiating or adjusting the dose of lipid-lowering medications as needed
- Signs and/or symptoms consistent with pancreatitis should prompt an appropriate clinical evaluation. Myalept metreleptin Online Cost
Monitor Closely (15)
- chlorpropamide
- glimepiride
- glipizide
- glyburide
- 1)insulin aspart
- 2)insulin detemir
- 3(insulin glargine
- 4)insulin glulisine
- 5)insulin lispro
- 6)insulin NPH
- insulin regular human
- nateglinide
- repaglinide
- tolazamide
- tolbutamide
Adverse Effects
>10%
- Headache (13%)
- Hypoglycemia (13%)
- Decreased weight (13%)
1-10%
- Abdominal pain (10%)
- Arthralgia (8%)
- Dizziness (8%)
- Ear infection (8%)
- Fatigue (8%)
- Nausea (8%)
- Ovarian cyst (8%)
- Upper respiratory tract infection (8%)
- Anemia (6%)
- Back pain (6%)
- Diarrhea (6%)
- Paresthesia (6%)
- Proteinuria (6%)
- Pyrexia (6%)
- Antibodies with neutralizing activity (6%)
- Injection site erythema and urticaria (4%) Order Myalept Powder Online
